Urban landscapes are growing quickly: by 2030, and as a result, globally, urbanization has become one of the largest causes for habitat degradation and loss; habitat that remains is dramatically altered with respect to a variety of parameters, including light, noise, temperature, and precipitation regimes. Here I present three sets of studies investigating these impacts on the behavior and physiology of reptiles and amphibians: 1) a field study of the impact of urban noise on tropical frog behavior; 2) a lab investigation of the impact of urban noise on tropical frog physiology; and 3) a combination of lab and field studies on the impacts of urbanization on the ecology and physiology of lizards in Oxy's back yard and across the Los Angeles Basin.